The MOUSE ANTI CAT CD134 Antibody from MyBioSource.com is a Mouse Monoclonal antibody to CD134, OX40, and Tnfrsf4. This antibody recognizes Human antigen. The MOUSE ANTI CAT CD134 Antibody has been validated for the following applications: Flow Cytometry, and Western Blot.
Description
Mouse anti Cat CD134 antibody, clone 7D6 recognizes feline CD134, otherwise known as OX40, a 43kDa type I membrane protein and member of the tumor necrosis factor receptor superfamily, expressed predominantly by CD4+ activated T cells, and a key regulator of T cell-dependent immune responses. CD134 has been identified as the receptor for the OX40 ligand, CD252, expressed by activated B cells, acting as a co-stimulatory signal for the stimulation and secretion of immunoglobulins. CD134 has also been identified as a binding receptor for Feline Immunodeficiency Virus (FIV), acting along with CXC chemokine receptor 4 (CXCR4) to facilitate the entry of the virus into CD4+ primary target cells